郭琦教授是中国国家天文台的研究员，同时也是国家天文台计算宇宙学重点实验室的副主任。她于2009年从慕尼黑大学获得博士学位，并在杜伦大学进行博士后研究。2013年，她被选入国家级青年科学家项目，并加入中国科学院国家天文台。现为基金委杰青。她的研究重点是星系宇宙学，在理论和观测方面都取得了一系列高水平的贡献。她曾获得2020年中国科学院青年科学家奖和2016年皇家学会牛顿高级学者奖。Dark matter and dark energy are among the most important cutting-edge sciences. Extensive global efforts have been dedicated to the large-scale structure evolution through projects like LSST, DESI, Euclid, PFS, and the Chinese space station optical survey. We have successfully completed a N-body cosmological simulation that traces 4 trillion particles from redshift 100 to the present day within a 2.5 Gpc/h box. The particle mass is 3.2 x 10^8 solar masses, meeting the requirements for the next generation of large-scale structure surveys. This simulation aids in understanding the systemic and statistical uncertainties involved in studying large-scale structure formation, including baryon acoustic oscillations, redshift distortion, weak lensing, high redshift AGNs and etc. In my presentation, I will delve into the details of the simulation and discuss advancements made in galaxy and AGN formation models.